Group housed | Socially isolated | F | p | |||||
---|---|---|---|---|---|---|---|---|
Baseline | 1-EBIO | Apamin | Baseline | 1-EBIO | Apamin | |||
Vm (mV) | -67.65 ± 0.77 | -67.07 ± 1.22 | -67.18 ± 1.07 | -66.71 ± 0.91 | -66.73 ± 1.17 | -65.9 ± 1.62 | 0.269 | 0.9288 |
Rin (MΩ) | 166.6 ± 16.78 | 145.6 ± 10.17 | 129.3 ± 12.94 | 183.3 ± 22.61 | 147.0 ± 15.72 | 156.5 ± 22.59 | 1.243 | 0.2985 |
Rheobase (pA) | 210.9 ± 17.12 | 212.1 ± 23.37 | 182.6 ± 21.18 | 190 ± 16.21 | 185.6 ± 25.08 | 154.7 ± 27.11 | 0.695 | 0.629 |
Ih (mV) | -4.98 ± 0.92 | -3.91 ± 0.81 | -4.71 ± 1.82 | -4.47 ± 0.42 | -5.52 ± 0.46 | -4.86 ± 0.75 | 0.6154 | 0.6886 |
AP peak (mV) | 78.59 ± 3.04 | 78.53 ± 3.06 | 74.42 ± 3.96 | 83.60 ± 1.65 | 85.96 ± 1.96 | 80.65 ± 3.50 | 1.884 | 0.1078 |
AP threshold (mV) | -44.95 ± 1.85 | -43.41 ± 1.72 | -43.42 ± 2.4 | -47.31 ± 1.80 | -44.43 ± 2.82 | -47.07 ± 1.58 | 0.7791 | 0.5682 |
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Shown is a summary of the effect of adolescent social isolation and SK channel modulators on other passive and active membrane properties of BLA pyramidal neurons. AP, Action potential.